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Bacterial Infection (Tyzzer Disease) in Dogs

Tyzzer Disease in Dogs

Tyzzer disease, stemming from the bacterium Clostridium piliformis, is a bacterial infection. It proliferates primarily in the intestines and upon reaching the liver, inflicts severe damage. The disease predominantly affects young dogs, putting them at significant risk.

Symptoms and Types

Because of the extent of liver damage, certain dogs afflicted with Tyzzer disease might succumb within 24-48 hours. Initial indications of the illness encompass:

  • Lethargy
  • Depression
  • Appetite loss
  • Diarrhea
  • Abdominal pain and discomfort
  • Liver enlargement
  • Abdominal distension
  • Reduced body temperature


Tyzzer disease is caused by the bacterium Clostridium piliformis.


Your veterinarian will gather a comprehensive medical history and conduct a physical examination of your dog. Following this, routine laboratory tests such as complete blood count, biochemistry profile, electrolyte panel, and urinalysis will be performed to evaluate your dog’s condition and the severity of the disease.

In cases of Tyzzer disease, the biochemistry profile testing may reveal elevated levels of liver enzymes, particularly as the dog’s condition worsens.


Regrettably, there exists no effective treatment for Tyzzer disease at present. It’s advisable to consult with your veterinarian to explore any options available to alleviate your dog’s discomfort.

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